Tamiflu vs. Xofluza: Which Flu Treatment Is Right for You?

Both medications are FDA-approved antiviral treatments for influenza, but they work differently and are used in different situations. Understanding the difference can help you get the fastest relief and best outcome when you have the flu.

What Is Tamiflu?

Tamiflu (oseltamivir) is a prescription antiviral medication that has been used for many years to treat influenza A and B.

How Tamiflu Works

Tamiflu blocks an enzyme called neuraminidase, which the flu virus needs to spread from cell to cell in your body. This helps shorten the duration and severity of symptoms.

How It’s Taken

• Taken twice daily for 5 days

• Available as capsules or liquid

• Can be used in adults, children, infants, and high-risk patients

Common Side Effects

• Nausea

• Vomiting

• Headache
  (Taking it with food often helps reduce stomach upset.)

What Is Xofluza?

Xofluza (baloxavir marboxil) is a newer antiviral medication for influenza A and B.

How Xofluza Works

Xofluza targets a different part of the virus, stopping it from replicating inside your cells. This halts the infection earlier in its course.

How It’s Taken

• Single-dose treatment

• Taken by mouth once

• Approved for patients 12 years and older (and certain younger patients depending on weight and guidelines)

Common Side Effects

• Diarrhea

• Bronchitis

• Nausea (generally mild)

Tamiflu vs. Xofluza: Key Differences

Which Flu Medication Is Better?

There is no one-size-fits-all answer. The best option depends on:

• How long you’ve had symptoms

• Your age

• Pregnancy status

• Medical conditions (asthma, diabetes, immune issues)

• Risk of flu complications

At EzMed Urgent Care, our medical providers evaluate each patient individually and prescribe the most appropriate antiviral based on current guidelines and your personal health history.

When Should You Start Flu Treatment?

Both Tamiflu and Xofluza work best when started within 48 hours of symptom onset. Early treatment can:

• Shorten illness duration

• Reduce symptom severity

• Lower the risk of complications like pneumonia

• Help you return to work or school sooner

If you think you have the flu, don’t wait.

Flu Testing and Treatment at EzMed Urgent Care

At EzMed Urgent Care, we offer:

• Rapid flu testing

• Same-day evaluation

• On-site prescriptions

• Treatment for adults and children

• Walk-in and convenient hours

If you’re experiencing flu symptoms, our experienced medical team is here to help you feel better—fast.

Final Takeaway

• Tamiflu is a trusted, multi-day antiviral ideal for many patients, including children and high-risk individuals.

• Xofluza offers the convenience of a single dose and works quickly when taken early.

• The right choice depends on you—and a medical evaluation makes all the difference.

For flu testing, treatment, and expert care, visit EzMed Urgent Care today.