Paxlovid for COVID-19 in 2026: Who Needs It and When It Helps

At EzMed Urgent Care, patients frequently ask whether Paxlovid is still needed and who should take it. Here’s what you should know.

What Is Paxlovid?

Paxlovid is an FDA-authorized oral antiviral medication used to treat mild to moderate COVID-19 in patients who are at risk for developing severe disease.

It consists of two medications:

• Nirmatrelvir, which blocks the virus from replicating

• Ritonavir, which boosts effectiveness by slowing medication breakdown

Together, they help reduce viral load early in infection.

Is Paxlovid Still Used in 2026?

Yes. Paxlovid is still prescribed in 2026 for select patients based on current clinical guidelines. While many people now experience milder COVID symptoms, certain individuals remain at higher risk for complications, hospitalization, or prolonged illness.

Paxlovid continues to show benefit when used early and appropriately.

Who May Benefit from Paxlovid?

Paxlovid is typically recommended for patients who:

• Are 50 years or older

• Have chronic conditions such as diabetes, asthma, heart disease, obesity, or immune suppression

• Are unvaccinated or not up to date on boosters

• Have a history of severe COVID illness

• Test positive for COVID and develop symptoms

A medical evaluation is essential to determine eligibility.

When Should Paxlovid Be Started?

Timing matters.

Paxlovid must be started within 5 days of symptom onset to be effective. Starting treatment early can:

• Reduce the risk of severe illness

• Lower hospitalization rates

• Shorten recovery time

• Decrease complications in high-risk patients

Waiting too long may eliminate the benefit.

How Is Paxlovid Taken?

• Taken twice daily for 5 days

• Oral tablets

• Requires review of current medications due to potential drug interactions

• Not recommended for certain kidney or liver conditions without dose adjustment

Because of these factors, Paxlovid should only be prescribed after a proper medical evaluation.

Paxlovid Side Effects

Most patients tolerate Paxlovid well. Possible side effects include:

• Metallic or bitter taste

• Nausea

• Diarrhea

• Temporary changes in taste

Serious side effects are uncommon when prescribed appropriately.

COVID Testing and Treatment at EzMed Urgent Care

At EzMed Urgent Care, we offer:

• Rapid COVID testing

• Same-day evaluation

• Medication review for Paxlovid eligibility

• Personalized treatment plans

• Care for adults and children

Our providers stay up to date with the latest treatment guidelines to ensure safe and effective care.

Final Takeaway

• Paxlovid remains a valuable COVID treatment in 2026

• It is most helpful for high-risk patients

• Early testing and evaluation are key

• Not everyone with COVID needs Paxlovid—but for the right patient, it can make a significant difference

If you’re experiencing COVID symptoms, visit EzMed Urgent Care for timely testing and expert guidance.